Mice and rats communicate in the ultrasonic frequency range, and it’s thought that cats evolved the ability to hear those high-pitched squeaks to better hunt their prey. Now, a new study suggests that sensitivity to higher pitched sounds may cause seizures in some older cats. After receiving reports of the problem, nicknamed the “Tom and Jerry syndrome” because of how the cartoon cat is often startled by sounds, researchers surveyed cat owners and examined their pets’ medical records, looking for insight into the types and durations of seizures and the sounds that provoked them. In 96 cats, they found evidence of the syndrome they call feline audiogenic reflex seizures. The most common types of seizure-eliciting sounds included crinkling tinfoil, clanking a metal spoon on a ceramic feeding bowl, and clinking glass. The severity of the seizure ranged from brief muscle jerks to more serious episodes where the cat lost consciousness and stiffened and jerked for several minutes, the researchers report online today in the Journal of Feline Medicine and Surgery. Both pedigree and nonpedigree cats were susceptible, although one breed was common: Thirty of the 96 cats were Birmans (pictured). Because the seizures coincided with old age—the average age of onset was 15 years—veterinarians could miss the disorder while dealing with the felines’ other health issues, the researchers say. Minimizing exposure to the problematic sounds and preliminary, therapeutic trials with levetiracetam—an anticonvulsant medication used to control epilepsy—among a small sample of the cats seemed to help limit the occurrence of seizures.